A middle age patient presented with groin mass.
Granular cell tumors are usually benign and complete excision is considered optimal therapy.
Females are more commonly affected than males.
Granular cell tumors are of probable schwanian cell origin and can be encountered in many sites including skin and subcutaneous tissue of the head and neck, oral, respiratory tracts, gastrointestinal and genitourinary tracts, visceral locations and female external genitalia.
The tumor is not encapsulated and arranged in variably sized nests and trabeculae of polygonal shaped cells with abundant coarsely granular pink cytoplasm. The cells have relatively small, uniform and hyperchromatic nuclei. Mitotic figures are absent. By immunohistochemistry, the lesional cells show expression of S100 protein.
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